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Brit J Pharmacol 9: 459462

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By putting everything into context by describing the BBB structure, emphasizing how the barrier alters in age and disease, and the current drugs explored to slow the negative outcomes of age and disease through acting directly on the BBB, the goal is to exploit the easily accessible and manipulable microbiota as a potential target to modulate the BBB

subsequent clinical resuscitation (e.g., fluid replacement, cooling) can gradually restore liver blood flow, a process that induces liver ischemiareperfusion injury (LIRI) [34]

However, in vivo and ex vivo research suggest that maternal diabetes may potentially dysregulate fetal glucocorticoid sensitivity