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To stay safer in surgery, always tell your surgical team and anesthesiologist about GLP-1 agonist medications you are taking, as well as all other medications and supplements

What is the evidence for pramlintide improving glycemic variability

The vagal afferents are implicated in the regulation of acute feeding behavior and long-term energy balance 5,6

In the gastrointestinal tract, GLP-1 delays gastric emptying through vagal activation and effects on smooth muscle, increases beta cell proliferation and survival as well as glucose-dependent insulin secretion, suppresses glucagon secretion, and reduces hepatic fat accumulation through fatty acid oxidation as well as hepatic gluconeogenesis [43]

Some people notice appetite changes quickly, while others need more time to adjust