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H.DyerD

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In contrast, a lower dose (275 mg/kg) enhanced antioxidant capacity and maintained metabolic balance

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Targeting the PPP, a major source of NADPH, in neuronal cell models has shown to summarize many of the cellular phenotypes concomitant with PD, such as increased oxidative stress, mitochondrial dysfunction, diminished GSH levels, and neuronal apoptosis [186]

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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doi: 10.1016/j.cell.2013.12.010 20 FujiiJHommaTKobayashiS

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