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Dopaminergic neurodegeneration could also be induced by intranigral administration of blood-borne molecules like histamine and thrombin [298, 299]

Sreenivasa M Y, Regina Sharmila Dass, A

This substantial participant database provides meaningful safety evidence across varied dosing regimens, administration routes (oral and injectable), and treatment durations, making it one of the more extensively studied peptide fragments in human clinical trials