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The Federal Circuit has found that claims directed to new results obtained with a known method are inherently anticipated and, therefore, unpatentable if practicing the known method would necessarily produce the claimed results

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[28] applied 100nM Ex-4to rat STRO-1-positive BMSC, which led to superior mineralization and osteoblast maturity

[DOI] [PubMed] [Google Scholar] 67.Severino P., DAmato A., Prosperi S., Costi B., Angotti D., Birtolo L.I., Chimenti C., Lavalle C., Maestrini V., Mancone M., et al