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Semaglutide, marketed as Ozempic for type 2 diabetes and Wegovy for chronic weight management, is a temperature-sensitive GLP-1 receptor agonist that requires specific handling
The cysteine residue on GSH renders it an important antioxidant that, in addition to its primary antioxidant capacities, acts as a substrate for the regeneration of other essential antioxidants [13,15,16]
This modification significantly improves oral bioavailability and stability without changing the peptide biological activity once it reaches target tissues
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