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Animals were subject to a timed-mating protocol, whereby prior exposure of females to dirty bedding from males allowed for stimulation and synchronization of the females estrous cycles through the Whitten Effect (Jemiolo et al, 1986)

Merrifield Resin 125 g (100mmol, 0.8mmol/g) is weighed, added to the compound 1 obtained above, reacted in N-methylpyrrolidone at 80 for 24 hours, filtered, the solid phase Resin is washed with DCM, then added with DCM solvent of 25% TFA and reacted at room temperature for 2 hours to obtain 1- (2-hydroxyethyl) imidazole Merrifield Resin without tert-butyl protection

The Conrad: 7600 Fay Avenue, La Jolla | Epstein Family Amphitheater: 9500 Gilman Drive, La Jolla A star-studded opening weekend is in store to kick off The Rady Shells summer season

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