4 A study of two participants cannot establish: The frequency of uncommon adverse events Safety across different ages or health conditions Safety with other medicines or substances Long-term safety Safety through other routes Clinical effectiveness The authors themselves stated that further studies were needed
However, doctors may recommend taking B12 supplements after the age of 50 years as your ability to absorb B12 decreases with age
professional B12 injections
At Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro (Sindh Province), efficacy of Sucrosomial B12 was compared with conventional formulated Evermin B12 (Methylcobalamin 1,000 g, manufactured by Global Laboratories and marketed by Reliance Pharma, Islamabad, Pakistan) & Neuromax B12 (Mecobalamin 1,000 g, manufactured by Bio Fine Pharmaceuticals, Multan, Pakistan)
Here are the realworld risk gaps: No standard dose or formulation Humans in papers got 20 mg IV in a pilot, but many online vendors sell subcutaneous vials without clear dosing guidance