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The difference isnt dramatic, but rates of nausea and diarrhea are modestly higher with tirzepatide compared to semaglutide in clinical trials

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It positively regulates microRNAs (miRNAs), such as miR-212-3p and miR-29c-5p, which control apoptotic pathways and APP processing

Schwartz LK, OKeefe SJ, Fujioka K, Gabe SM, Lamprecht G, Pape UF, et al

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