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10.1016/0304-4165(70)90185-6 Biochim

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A meta-analysis reported a pooled risk ratio of 2.83 for continuous abstinence at 52 weeks compared with placebo [] , while a network meta-analysis similarly found that varenicline nearly doubled the likelihood of sustained cessation []

On the whole, reasons for semaglutide differences are not fully understood and warrant further research, especially studies of real-world weight loss with semaglutide that include people without type 2 diabetes, like this one

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