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Nonetheless, severe or persisting adverse reactions such as movement disorders should be given medical attention without delay if they manifest

The metabolism of the branched-chain amino acids is critical to overall nitrogen homeostasis in the brain and to the maintenance of proper levels of the excitatory neurotransmitter, glutamate

Notably, butyryl-CoA competitively binds to carnitine palmitoyltransferase 1 A (CPT1A), thereby alleviating the inhibitory effect of malonyl-CoA on CPT1A activity [51]

Strength training and weight-bearing activity may help reduce this risk