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From a scientific perspective, exenatides approval proved the validity of GLP-1 receptor agonism as a therapeutic strategy ( [99] ) ( [100] )

A number of mechanisms have been proposed to underlie the proatherogenic properties of sdLDL, including increased susceptibility of oxidation (464) and glycation (465), promoting arterial retention and increased macrophage foam cell formation

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Drugs vs Network Repair Semaglutide (Ozempic) GLP-1 receptor agonist Tirzepatide Dual GIP + GLP-1 agonist These drugs force receptor activation