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Nutrient deficiencies: Appetite suppression can significantly reduce intake of essential vitamins and minerals

85 observed significant lumbar BMD increases (2.89% at six months, 5.7% at one year, 7.9% at two years), potentially linked to improved vitamin D levels and reduced parathyroid hormone (PTH)

2c) but it is notable that the inhibitory effect of GLP-1(736) (10 pmol/l) was reduced by exendin(939), indicating that part of GLP-1(736)s action is mediated by GLP-1R (possibly via stimulation of somatostatin secretion

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In commercially available mouse and human primary caECs, we also observed robust cAMP responses to GLP-1(2836) (Figure 3B)