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Common reasons include: Pernicious anemia , an autoimmune condition affecting intrinsic factor production Gastrointestinal disorders, such as Crohns disease or celiac disease Prolonged use of certain medications, like proton pump inhibitors Knowing these causes helps spot at-risk people

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(Moench): Traditional claims and scientific evidences

Although the synthesized melanin was aggregated within one hour, the aggregation was inhibited by the addition of glutathione