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Therapeutic Modulation of GABAergic Signaling The therapeutic potential of modulating GABAergic transmission is significant, particularly in the treatment of seizure disorders, anxiety, and certain neurodegenerative diseases

(2022, October 2)

Melatonin reprograms metabolism and impairs mitochondrial function in activated ILC2s Immune cells often rely on the coalescence of diverse metabolic pathways, which provide cells with the energy, reactive metabolites and essential cofactors needed to sustain high levels of activity in pro-inflammatory states

Disturbances in glutamate-mediated neurotransmission have been increasingly documented in a range of neuropsychiatric disorders including schizophrenia, substance abuse, mood disorders, Alzheimer's disease, and autism-spectrum disorders