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The discovery of liver stem cells or progenitor cells marked a significant advance, offering new avenues for therapy

10.4103/0253-7613.115015 179 WangT.JianZ.BaskysA.YangJ.LiJ.GuoH.et al (2020a)

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This is particularly important when the preparation methods diverge from traditional practices, such as using organic solvents instead of aqueous ones