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Who should not use it without physician consultation, per the label Anyone who is pregnant, nursing, under 18, or currently under treatment for a medical condition

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Common gastrointestinal side effects are the most frequently reported adverse reactions, particularly during treatment initiation and dose escalation: Nausea (affecting 2040% of patients initially) Vomiting and diarrhoea Constipation Abdominal discomfort or bloating These symptoms typically diminish over several weeks as tolerance develops