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The association of ROS with neuronal degeneration in PD is further substantiated by modeling the Parkinsonian phenotypes in animals through 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, 1,1-dimethyl-4,4-bipyridinium dichloride (paraquat), or 6-hydroxydopamine (6-OHDA), those are known of elevate the oxygen free-radicals in the cell 18

doi:10.11604/pamj.2021.38.237.20967

Standards and quality controls were prepared by spiking L2-Cmu into mouse plasma

[11] As a result, patients on thyroid medication should have their thyroid function monitored if ALA is added, and dosing of thyroid medication may need to be adjusted by their doctor

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