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The aging process of skin is not only affected by internal and time, but also by external environmental factors such as ultraviolet rays, air pollution, smoking, and malnutrition, which will accelerate skin aging and increase the number of senescent cells in the skin (22)

Similar studies have been performed in various other groups, including obese patients

The difference between 95% and 99% purity might seem small, but that 4% represents impurities that can include unreacted precursors, truncated sequences, degradation products, and synthesis byproducts

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Its not considered painful, and the discomfort lasts just a few seconds