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Most patients achieve therapeutic benefits with 250-500 mcg daily, administered subcutaneously in the abdomen, thigh, or arm

Dose escalation is not always better starting low (300 mcg) and adjusting as needed is recommended

10.1016/j.neuropharm.2008.07.031 Neuropharmacology 176 ZhuX.RainaA

Article PubMed Google Scholar Lu JCY, Dengler J, Poppler LH et al (2020) Identifying common peroneal neuropathy before foot drop

the biological barriers in the liver reduce the amounts of drugs that enter the body circulation, inhibiting the therapeutic effect of the drugs [11, 12]

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