This avoids potential interactions between the copper peptide and retinoid in the same application
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This is anecdotal and not clinically validated
Intravenous injection of bufatalin to mice in dose 6 mg/kg increased its levels in plasma up to 5 g/mL (11 ) in 5 min, but it bounced back quickly due to lower T 1/2 = 28.6 min) (Yu and Hou, 2011)