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Despite its ubiquity and recognized safety when taken within recommended doses, APAP overdose remains a significant public health concern worldwide due to liver injury, posing a substantial burden on healthcare systems and contributing to a considerable number of hospitalizations and fatalities annually

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It operates through a relatively small number of interconnected biochemical systems: mitochondrial energy metabolism membrane lipid structure antioxidant defense networks methylation chemistry neurotransmitter signaling mineral dependent enzyme activity RELATED: OPEN PART 2 OF THIS ARTICLE TO READ LATER When a nutrient participates in one of these systems, the body can actually use it