Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge M-P, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M (2023) OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases
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Therefore, in contrast to prescription and newer over-the-counter medications, herbal products in the United States are usually marketed without the benefit of clinical trials to demonstrate either efficacy or safety (World Health Organization, 2005)
This information is valuable as it reflects the experiences of patients in real-life settings, providing a more comprehensive understanding of the medications safety profile
For reconstitution studies, use sterile bacteriostatic water under appropriate laboratory controls, then store reconstituted material at 28C and use within 14 days