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It involves, as a first step, lifestyle modifications, blood pressure and lipid control, together with the combination of different pharmacological treatments (Fig

Farxiga (dapagliflozin) is a prescription drug, commonly taken as a 10 mg oral tablet once daily, to lower blood glucose levels in Type 2 diabetes mellitus, reduce the risk of hospitalization and cardiovascular death in congestive heart failure (CHF), and lower the risk of progression of chronic kidney disease (CKD)

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The kidneys may regulate bodily fluid volume and vascular resistance by directly altering renal tubular transport of fluid and sodium or indirectly, by altering renal hemodynamics or endocrine factors 5,6