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In contrast, the in vitro reduction of Escherichia coli RNR or PR was shown to require both active-site cysteinyl residues of glutaredoxin 1 (EcGrx1) 41,57

Notably, dexamethasone, a potent corticosteroid, was ineffective in restoring normal epidermal morphology in the same study

Secondary outcomes were the impact on basic semen parameters (sperm concentration, progressive sperm motility, total sperm motility, sperm morphology using the percentage of normal sperm forms), SDF, and indices of seminal OS such as seminal total AOX capacity (TAC) and malondialdehyde acid (MDA)

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Korkushko O, Khavinson VK, Shatilo VB, Antonyuk-Shcheglova IA: Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects with accelerated aging