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Findings of the prespecified analysis of the trial, published in The Lancet, suggest that semaglutide and possibly other glucagon-like peptide-1 receptor agonists (GLP-1Ras) should be reconceptualised as disease-modifying treatments rather than solely medications for glycaemic control or weight loss, the studys authors have suggested

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But the fact that so many patients perceive a difference in both effectiveness and side effects means this remains a hotly debated topic online