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Mechanisms of Action of GLP-1 in the Pancreas

While liraglutide 3 mg (Saxenda) is licensed by the MHRA for weight management, it is not currently recommended by NICE for routine NHS commissioning

Over the past century, scientific advances have progressively shaped the landscape of GLP-1 research, from the early discovery of the incretin effect and preproglucagon gene structure to the clinical development of GLP-1 receptor agonists (GLP-1RAs) and, more recently, nanotechnology-based drug delivery systems

Once the GLP-1s came out, they truly helped so many patients with metabolic disorders, especially diabetes and obesity, become healthier and improved the quality of their lives, Ganta says

However, a chasm is present for large scale studies to see the role GLP-1RA in neurological diseases including ocular pathologies, present studies are inconclusive about the implications in long term preventions in different populations