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Specifically, genistein decreased the recruitment of primordial cells and increased the number of mature follicles and corpora lutea by upregulating ovarian SOD and GSH levels, and downregulating IL-1 and MAD levels, which means preservation of ovarian function and follicular reservoirs (Saleh and Mansour, 2016)

Individuals may also opt for over-the-counter medications or topical creams for relief

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The assumption that injectable bioavailability produces superior outcomes to what topical studies show is mechanistically plausible but not directly confirmed in controlled human trials

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