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Preclinical studies show reductions in caloric intake and fat accumulation, suggesting its role in experimental research on metabolic regulation, obesity, and neuroendocrine energy homeostasis

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However, Aja and colleagues found no evidence for this hypothesis since in this model CPT-1 should inhibit feeding by increasing cytosolic fatty-acyl CoA levels while they actually showed the initial response of mice to a CPT-1 inhibitor was an increase in appetite [75]

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Woo J, Kim SH, Han K, Choi M

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Die Autoren stufen die Substanz deshalb ausdrcklich als experimentell ein

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