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J., Grundmann, O., & Johnson-Mallard, V

Excessive ROS generated by the electron transport chain damages mitochondrial membranes, proteins, and DNA, while impaired calcium handling increases cytosolic and mitochondrial Calcium (Ca 2+) levels, further compromising bioenergetics ( 2+ overload enhances ROS production by stimulating dehydrogenases and destabilizing ETC function

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PlexusDx recommends using a refrigerator thermometer to monitor your storage environment and keep medications in the main body of the fridge rather than on the door, where temperature fluctuations are more extreme