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4.5 Pharmacokinetic, tissue distribution, and excretion studies in rats administered radioactive-labeled BPC157 Thirty intact SD rats, six JVC rats, and six BDC rats (half male and half female subjects) were injected intramuscularly with 100 g/300 Ci/kg of [3H]BPC157

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This activation reduces the inhibitory binding between Caveolin-1 and eNOS, allowing greater eNOS activation and nitric oxide productionwith laboratory studies showing BPC-157 at 1 g/ml increases NO production 1.35-fold compared to controls

Observational | Animal | In vitro Stable gastric pentadecapeptide BPC 157: protective effects and healing mechanisms Animal | In vitro What is BPC-157