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Researchers compare tirzepatide and semaglutide in largest real-world study Two medications, semaglutide and tirzepatide, have become widely used because they lower blood sugar and support weight loss

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Unlike earlier weight-management treatments that target a single hormone receptor, retatrutide simultaneously activates three distinct receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor

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