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Der amerikanische Biochemiker Loren Pickart entdeckte es 1973, als er beobachtete, dass Lebergewebe lterer Patienten in Gegenwart von Plasma jngerer Spender eine verbesserte Proteinsynthese zeigte

115 Aortic valve stenosis (AVS) is characterized by leaflet calcification and stiffening, eventually inducing left ventricular obstruction and ischaemic injury