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After the 6-wk chronic ethanol feeding, the most striking difference between WT and KO mice was the complete prevention of steatosis development in KO mice

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137 CYP2E1 overexpression triggers ROS accumulation, enhancing the interaction between disheveled segment polarity protein 2 (Dvl2) and Kelch-like protein 12 and thereby inducing the ubiquitination and degradation of Dvl2 and suppressing tumor growth via Wnt/-catenin signaling

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It should be noted that selenomethionine accumulates at much higher levels in the body than other forms of selenium

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doi: 10.4149/endo_2014_01_35 17

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