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tirzepatide adds GIP

For MCAS and year-round histamine issues, longer-term protocols are more common

concurrent use may compound the risk of kidney stones or acidosis

Throughout the STEP trials, participants responded to the Patient Health Questionnaire and ColumbiaSuicide Severity Rating Scale to gauge depressive symptoms and suicidal ideation and behavior, respectively

Gradual incorporation of soluble fiber (oats, psyllium, legumes) and insoluble fiber (whole grains, vegetables, wheat bran) to achieve recommended daily intake (approximately 25g for women, 38g for men) can significantly improve stool consistency and frequency