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These agents work through several complementary mechanisms that improve metabolic control

Non-prescription and compounded peptides such as BPC-157, CJC-1295/Ipamorelin, AOD-9604, and MOTS-c are not FDA-approved for weight loss and lack the same regulatory oversight and clinical safety data as the GLP-1 drugs in the table above, which is why they should only be used under the guidance of a licensed medical provider who can order lab work, personalize dosing, and monitor for side effects throughout treatment

The science behind the triple agonist: GLP-1, GIP, and Glucagon Retatrutide (LY3437943) is a next-generation triple receptor agonist drug that activates three receptors (GLP-1, glucagon, and GIP receptors) simultaneously

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GLP-1 is viable for long-term use for patients who wish to lose excess weight