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Comment: Many commenters were concerned about the proposed ASM overlap with the Shared Savings Program, noting concerns that allowing overlapping participation in both models could create conflicting incentives, duplicative penalties, increased administrative burdens, and fragmentation of care

The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]

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At 5mg/ml, 10 units equals 0.5mg