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Kevin Klatt, PhD, RD, an assistant research scientist and instructor in the Department of Nutrition Sciences and Toxicology at University of California, Berkeley, cautions that epidemiological studies using circulating levels of nutrients or metabolites as proxies for dietary exposure often dont correlate with randomized controlled trials that aim to increase levels of those nutrients or metabolites

Reduced blood flow due to cardiovascular diseases Vascular conditions like peripheral artery disease Shock or severe dehydration These issues can make it hard for the body to keep its lips their normal color by cutting down on blood flow and oxygen

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