facts about glutathione and parkinson's disease Central nervous system uptake of intranasal in The Role of Oxidative Stress

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In section VII.I.5.d(3)

Nitric Oxide System Interaction A third, less extensively characterised mechanism involves potential interaction with the nitric oxide (NO) system a signalling pathway involved in vascular tone, inflammation modulation, and various tissue processes

But the starting numbers differ because the products differ

It's pretty rare to overdose on B12 since it's water-soluble, but super high doses can cause side effects