does glp-1 help with inflammation If Drugs Are Good For Everything, Should We All Be on Them? Anti-Inflammatory Effects of GLP-1-Based Therapies

Rosanoff A et al

Intestinal fat cannot be removed by liposuction because it would be too dangerous

Pharmacokinetics: Bioavailability: ~90% Half-life: ~2430 hours Metabolism: Minimal hepatic metabolism Excretion: Mainly renal Adverse Effects: Headache Nausea Abdominal pain Diarrhea Interesting Fact: Unlike older prokinetic agents (like cisapride), prucalopride has high receptor selectivity, reducing the risk of cardiac arrhythmias a major safety improvement

Urine (0.5-1 mL) reolects renal clearance rather than mitochondrial ounction

It is built on a guiding principle of using the lowest effective dose first