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What to expect during the transition The first 2-4 weeks after switching often involve a temporary reduction in appetite suppression

This can help reduce overall calorie intake, leading to weight loss

Completion of an online assessment does not establish a doctorpatient relationship, which is formed only after clinical review and acceptance by a licensed NexLife-affiliated provider

Regular exercise is also considered beneficial, especially in amplifying the effects of the injections

Efficacy comparison by clinical trial data The most relevant head-to-head data comes from the SURPASS-2 trial (tirzepatide vs semaglutide 1 mg for type 2 diabetes) and the SURMOUNT-5 trial (tirzepatide vs semaglutide 2.4 mg for obesity)