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It is used in performance driven protocols designed to help maximise results from training while improving recovery

When you lose weight, your body responds by increasing ghrelin (the hormone that makes you feel hungry) and decreasing leptin (the hormone that signals fullness)

It's worth noting that very rapid weight loss or extremely low energy availability should be avoided, as these can exacerbate menstrual disturbances

The Phase 2b data showing competitive weight loss is encouraging, and Pfizer's acquisition of Metsera underscores commercial confidence in the concept