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Ethics declarations Ethics approval and consent to participate The study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines and received ethical approval from the Institutional Review Board of Chung Shan Medical University Hospital (IRB number: CS2-21176)

BOXED WARNING Risk of Thyroid C-cell Tumors In animal studies, Ozempic caused thyroid tumors, and it is not known if this happens in people as well

In the present study, diabetes was induced using STZ at a dose of 60 mg/kg [17,18]

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In addition to these effects, GLP-1s have the added advantage of slowing gastric emptying