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Plasma PYY 336 , endogenous GLP-1, glucose, ghrelin and serum insulin meal responses The PYY 336 levels during the meal test were significantly higher at week 52 for the GLP-1RA group compared with the control group, P 0.05

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Originally approved for diabetes, GLP-1 drugs are positively used in the management of weight loss, cardiovascular risk, fatty liver disease, and neurodegenerative conditions

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Current evidence suggests that modulation of EAT may serve as a key mediating pathway for the cardioprotective effects of GLP-1RAs, and this area warrants further investigation