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High chemical diversity, biochemical specificity and several other molecular properties of the drugs obtained from natural products make them favourable for the treatment of nerve injuries and associated symptoms such as neuropathic pain [173, 174]

Rice, a silicon-accumulating crop, stores more than 10% silica in its stem and leaf dry weights, which is ten times greater than that of nitrogen and twenty times greater than that of phosphorus [20, 21]

Previous research studies have found that the activity of mitochondrial respiratory complex I in substantia nigra pars compacta of PD patients decreases and destroys the electron transport chain, which may lead to the excessive production of ROS and induce apoptosis 41

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