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Though remarkably effective, bariatric surgery carries the limitations inherent to any invasive procedure (surgical complications, cost, access): it is hard to imagine tens of millions of obese individuals going under the knife each year

Merck began trials of the HMG-CoA reductase inhibitor lovastatin in 1980, and won a historic approval in 1987-- showing the medication produced robust reductions in LDL levels

Treatment suitability and results vary by individual

There is an urgent need for noninvasive tests (NITs) to identify eligible patients accurately without the need for invasive liver biopsies