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In addition, aberrant Ca 2+ signaling causing mitochondrial dysfunction can adversely affect neurotransmitter signaling and lead to excitation/inhibition imbalance [94, 97, 98]

This is especially important during periods of weight loss, as rapid changes can impact bone density over time

Plasma was stored at 80 C until analysis

This method was also applied to influenza A virus 231 , and generated safe and effective live-attenuated vaccines that elicited robust protective immune responses in animal models, suggesting that ncAA-mediated live-attenuated vaccine is a generally applicable approach