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Several studies indicate that carnitine supplementation ( 2 ~ 3 grams/day for 3 ~ 4 months) may improve sperm quality and volume.

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A recent meta-analysis study reviewed twelve randomized controlled trials (RCTs) (n = 791) and found that ALC supplementation significantly reduced depressive symptoms in MDD as monotherapy and augmentation compared to placebo, with effect sizes comparable to standard antidepressants and a superior safety profile