Ferroptosis inducers can directly or indirectly affect glutathione peroxidase through different pathways, resulting in a decrease in antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in cells, ultimately leading to oxidative cell death (Li et al., 2020)
Theres also encouraging animal data suggesting it might speed up injury recovery
However, numerous studies use different nutrient combinations, which generally comprised those that supported mitochondrial bioenergetic and antioxidant networks, including vitamin Bs, vitamin C, vitamin E, selenium, zinc, lipoic acid, L-carnitine, and taurine [175]
Materials and methods Cell culture The K-562 and Lenti-X 293T cells were purchased from the American Type Culture Collection (CCL-243, ATCC) and Clontech (#632180), respectively
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