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In addition, there may be potential that these fragments are binding to these same receptors to elicit a zonulin-like effect in tight junction dysregulation, versus an inhibition of zonulin activity, although mechanistic studies need to be conducted to fully explore this possibility

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Zhang Y, Breevoort SR, Angdisen J, Fu M, Schmidt DR, Holmstrom SR, et al

Oxidative stress increases lesions and adhesions via the production of endothelial growth factor which promotes angiogenesis (blood vessel formation) to the Endometriosis